Sensitive Determination of 4-n-Nonylphenol in Domestic Wastewater and Liquid Detergent by Binary Solvent Microextraction (BSME) and Gas Chromatography-Mass Spectrometry (GC-MS) with Matrix Matching Calibration

Erarpat S. , Bodur S., Chormey D. S. , Öz E. , Bakırdere S.

ANALYTICAL LETTERS, 2021 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2021
  • Doi Number: 10.1080/00032719.2021.1985511
  • Title of Journal : ANALYTICAL LETTERS
  • Keywords: 4-n-nonylphenol, binary solvent microextraction (BSME), environmental chemistry, gas chromatography-mass spectrometry (GC-MS), water quality, SOLID-PHASE MICROEXTRACTION, BISPHENOL-A, NONYLPHENOL, PESTICIDES, SAMPLES, DESIGN, RIVER


Binary solvent microextraction (BSME) coupled to gas chromatography-mass spectrometry (GC-MS) was employed to determine 4-n-nonylphenol in domestic wastewater and detergent. The developed BSME method was applied to obtain lower detection limits by preconcentrating the analyte before determination by GC-MS. Relevant parameters of the extraction method, including the binary solvent volume, dispersive solvent volume, and vortex period, were optimized using Box-Behnken Design. Under the optimum conditions, the limit of detection (LOD), limit of quantitation, and linear dynamic range were 0.6, 2.0, and 2.0 to 100 ng g(-1), respectively. The extraction procedure provided an approximate 470-fold enhancement in the detection power. Recovery experiments were performed for spiked wastewater and detergent by performing matrix matching calibration. The recoveries obtained by BSME-GC-MS for wastewater and detergent were between 94 and 103% and 91 and 109%, respectively.