The purpose of this study is to evaluate the effect of CIS Building Integrated Photovoltaic as a shading device on building energy performance and PV life cycle. A multi-faceted BIPV energy evaluation approach is created. Energy performance is evaluated in two climate regions, in three scenarios for two transparency ratios of an office building. The case study indicated that when BIPV was used, in mild climates there was 24.82–41.05%, and in hot climates, 35.21–56.18% net energy consumption decreased. The PVs can produce 6.5–9.1 times the amount of energy consumed during manufacturing over the usage period. Finally, it was shown that the CIS technology contributes to sustainable architecture by reducing the integrated design difficulties in front of BIPV.