© 2021 Elsevier LtdThis study introduces a forecasting model to help design an effective blood supply chain mechanism for tackling the COVID-19 pandemic. In doing so, first, the number of people recovered from COVID-19 is forecasted using the Artificial Neural Networks (ANNs) to determine potential donors for convalescent (immune) plasma (CIP) treatment of COVID-19. This is performed explicitly to show the applicability of ANNs in forecasting the daily number of patients recovered from COVID-19. Second, the ANNs-based approach is further applied to the data from Italy to confirm its robustness in other geographical contexts. Finally, to evaluate its forecasting accuracy, the proposed Multi-Layer Perceptron (MLP) approach is compared with other traditional models, including Autoregressive Integrated Moving Average (ARIMA), Long Short-term Memory (LSTM), and Nonlinear Autoregressive Network with Exogenous Inputs (NARX). Compared to the ARIMA, LSTM, and NARX, the MLP-based model is found to perform better in forecasting the number of people recovered from COVID-19. Overall, the findings suggest that the proposed model is robust and can be widely applied in other parts of the world in forecasting the patients recovered from COVID-19.