Synthesis of New Thiazolidine Based Organocatalysts and their Application to Asymmetric Aldol Reaction

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Cicek M., Aydoğan F., Yolaçan Ç.

LETTERS IN ORGANIC CHEMISTRY, vol.14, pp.778-786, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 14
• Publication Date: 2017
• Doi Number: 10.2174/1570178614666170724125842
• Journal Name: LETTERS IN ORGANIC CHEMISTRY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.778-786
• Yıldız Technical University Affiliated: Yes

Abstract

Background: Proline and its derivatives are versatile organocatalysts for many reactions. Especially prolinamide derivatives have been prepared and investigated in aldol reaction successfully. Generally, derivatizations have been made on side chain of proline to develop new effective catalysts. But, there are only few examples of different cyclic systems other than pyrrolidine ring used as chiral organocatalysts.