Copy For Citation
MUTLU Ö., Turgut-Balik D.
BALKAN MEDICAL JOURNAL, vol.29, no.4, pp.364-369, 2012 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
29
Issue:
4
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Publication Date:
2012
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Doi Number:
10.5152/balkanmedj.2012.047
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Journal Name:
BALKAN MEDICAL JOURNAL
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
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Page Numbers:
pp.364-369
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Keywords:
Lactate dehydrogenase, Plasmodium vivax, antimalarial drug, site-directed mutagenesis, kinetic analysis, DEHYDROGENASE GENE, FALCIPARUM, EXPRESSION, PARASITE, MALARIA, CLONING
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Yıldız Technical University Affiliated:
Yes
Abstract
Objective: In this study, kinetic analysis was performed to understand the functional importance of the amino terminal of the active site of previously mutated Plasmodium vivax Lactate Dehydrogenase enzyme by mimicking Toxoplasma gondii I, II, Eimeria acervulina and Eimeria tenella LDH's.