Correlation between Na/K ratio and electron densities in blood samples of breast cancer patients

Topdağı Ö., Toker O., Bakırdere S., Bursalioglu E. O., Öz E., Eyecioglu O., ...More

BIOMETALS, vol.31, pp.673-678, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31
  • Publication Date: 2018
  • Doi Number: 10.1007/s10534-018-0118-2
  • Journal Name: BIOMETALS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.673-678
  • Yıldız Technical University Affiliated: Yes


The main purpose of this study was to investigate the relationship between the electron densities and Na/K ratio which has important role in breast cancer disease. Determinations of sodium and potassium concentrations in blood samples performed with inductive coupled plasma-atomic emission spectrometry. Electron density values of blood samples were determined via ZXCOM. Statistical analyses were performed for electron densities and Na/K ratio including Kolmogorov-Smirnov normality tests, Spearman's rank correlation test and Mann-Whitney U test. It was found that the electron densities significantly differ between control and breast cancer groups. In addition, statistically significant positive correlation was found between the electron density and Na/K ratios in breast cancer group.