Akademik Veri Yönetim Sistemi
Çukurova University Journal of the Faculty of Engineering and Architecture, cilt.33, sa.2, ss.237-241, 2016 (Hakemli Dergi)
The aim of the present study was to investigate the effect of chitosan modification of silicon urethral
catheters to improve antibacterial activity against to biofilm formation for long term catheterization.
Chitosan was first immobilized on the silicon surface through a (3-aminopropyl) triethoxysilane (APTES)
bridge in ethanol, toluene and acetone solutions, and glutaraldehyde used as cross linker. Fourier
Transform Infrared Spectroscopy and Scanning Electron Microscopy were used for imaging surface
modifications and characterization of silicone catheters. Biodegradability of chitosan hydrogel coatings
was investigated with using artificial urea solution through pH measurements. The results showed that
successful formation of chitosan hydrogels at catheter surface was observed both silicone urinary
catheters