Role of biomaterials in prevention of in-stent restenosis


Lacin N. , Utkan G. G.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, vol.102, no.5, pp.1113-1120, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 102 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.1002/jbm.b.33083
  • Title of Journal : JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
  • Page Numbers: pp.1113-1120

Abstract

Coronary balloon angioplasty and coronary stenting are the procedures used in healing coronary artery disease. However, injury of arteries during angioplasty and stenting causes cell stimulations in tissue. Cell movement and thrombosis lead to re-narrowing of widened vessel called restenosis. Several new types of carriers and technology have been developed to suppress and/or prevent restenosis. Authors review the polymeric materials featured in drug/gene carrier systems, nanovehicles, and stent coating materials against restenosis. (C) 2013 Wiley Periodicals, Inc.