Magnesium doping on TiN coatings affects mesenchymal stem cell differentiation and proliferation positively in a dose-dependent manner


ÖNDER S. , Calikoglu-Koyuncu A. C. , Kazmanli K., Urgen M., Kök F. N. , Torun-Kose G.

BIO-MEDICAL MATERIALS AND ENGINEERING, cilt.29, ss.427-438, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3233/bme-181000
  • Dergi Adı: BIO-MEDICAL MATERIALS AND ENGINEERING
  • Sayfa Sayıları: ss.427-438

Özet

BACKGROUND: In vitro evaluation of cell-surface interactions for hard tissue implants have mostly been done using osteoblasts. However, when an implant is placed in the body, mesenchymal stem cells (MSCs) play a major role in new bone formation. Therefore, using MSCs in cell-surface investigations may provide more reliable information on the prediction of in vivo behavior of implants.