Bacterial Cellulose Based Membranes for Artificial Kidney Applications


Çalhan A., Küçük İ., Gündüz O., Eren F., Hasanoğlu A.

8th International Symposium on Membrane Technologies and Applications (MEMTEK 2025), İzmir, Turkey, 12 - 14 November 2025, pp.254-255, (Full Text)

  • Publication Type: Conference Paper / Full Text
  • City: İzmir
  • Country: Turkey
  • Page Numbers: pp.254-255
  • Yıldız Technical University Affiliated: Yes

Abstract

In this study, bacterial cellulose (BC) and ZIF-8-incorporated BC (BC/ZIF-8) membranes were fabricated and systematically evaluated for water permeability, urea, creatinine, and protein adsorption, hemocompatibility, and antibacterial performance. The incorporation of ZIF-8 enhanced water permeability (0.13 to 0.24 ml.cm-2min-1.bar-1) and significantly improved creatinine adsorption due to the increased porosity and molecular sieving effect. BSA adsorption remained low, indicating reduced protein fouling and good blood compatibility. Hemocompatibility tests with platelet-rich plasma confirmed that the membranes exhibited excellent blood compatibility without inducing hemolysis. Antibacterial assays demonstrated inhibition only against Staphylococcus aureus, suggesting that ZIF-8 imparts selective antibacterial activity toward Gram-positive bacteria