Prevention of cyclophosphamide-induced hemorrhagic cystitis by resveratrol: a comparative experimental study with mesna

Keles I., Bozkurt M., CEMEK M., Karalar M., Hazini A., Alpdağtaş S., ...More

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.46, no.12, pp.2301-2310, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 12
  • Publication Date: 2014
  • Doi Number: 10.1007/s11255-014-0833-8
  • Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2301-2310
  • Yıldız Technical University Affiliated: Yes

Abstract

Hemorrhagic cystitis (HC) is the most common urotoxic side effect of cyclophosphamide (CP). The aim of this study was to compare the classical efficacy of mesna (2-mercaptoethane sulfonate sodium) with three different doses of resveratrol (RES) on cyclophosphamide-induced HC in rats.