(+)-CSA Catalyzed Multicomponent Synthesis of 1-[(1,3-Thiazol-2-ylamino)methyl]-2-naphthols and Their Ring-Closure Reaction under Ultrasonic Irradiation


Pelit E., TURGUT Z.

JOURNAL OF CHEMISTRY, 2016 (SCI İndekslerine Giren Dergi)

  • Cilt numarası:
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1155/2016/9315614
  • Dergi Adı: JOURNAL OF CHEMISTRY

Özet

New 1-[(1,3-thiazol-2-ylamino)methyl]-2-naphthols were obtained by condensation of 2-aminothiazole, aromatic aldehydes, and 2-naphthol in the presence of (+)-camphor-10-sulfonic acid ((+)-CSA) as an effective catalyst under ultrasound-promoted solvent-free conditions. The 1-[(1,3-thiazol-2-ylamino) methyl]-2-naphthol derivatives were converted in ring-closure reaction with formaldehyde to the corresponding naphthoxazine derivatives.