Quantifying Heterogeneity in Emphysema from High-Resolution Computed Tomography: A Lung Tissue Research Consortium Study

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Yilmaz C., DANE D. M. , PATEL N. C. , HSIA C. C. W.

ACADEMIC RADIOLOGY, vol.20, no.2, pp.181-193, 2013 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1016/j.acra.2012.09.013
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.181-193


Rationale and Objectives: To quantify spatial distribution of emphysema using high-resolution computed tomography (HRCT), we applied semiautomated analysis with internal attenuation calibration to measure regional air volume, tissue volume, and fractional tissue volume (FTV = tissue/[air + tissue] volume) in well-characterized patients studied by the Lung Tissue Research Consortium (LTRC).