THE STUDY OF SYNTETIC PEPTIDE LOADED PLGA NANOPARTICLES CYTOTOXICITY IN VITRO

DERMAN S., AKDESTE Z. M., Ates S. C., MANSUROĞLU B., Kizilbey K., BAĞIROVA M., ...More

FRESENIUS ENVIRONMENTAL BULLETIN, vol.26, pp.1646-1653, 2017 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 26
  • Publication Date: 2017
  • Journal Name: FRESENIUS ENVIRONMENTAL BULLETIN
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.1646-1653
  • Yıldız Technical University Affiliated: Yes

Abstract

Canine parvovirus (CPV) is a viral disease which is seen widely worldwide and infects puppies. Current vaccines which developed against this infection have several disadvantages. The antigenic property of different peptide sequences on VP2 capsid protein which belongs to CPV has been shown in different studies. However, carriers or adjuvants are also required for peptide antigens which have small molecular size and weak immunogenicity.