Ibuprofen release from porous hydroxyapatite tablets

ÖNER M., Yetiz E., Ay E., Uysal U.

CERAMICS INTERNATIONAL, cilt.37, sa.7, ss.2117-2125, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 7
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.ceramint.2011.02.021
  • Dergi Adı: CERAMICS INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2117-2125
  • Anahtar Kelimeler: Biomedical applications, Hydroxyapatite, Drug release, Ibuprofen, CALCIUM-PHOSPHATE CEMENT, DRUG-DELIVERY SYSTEM, MIXING SOLUTION VOLUME, IN-VITRO, INDOMETHACIN RELEASE, TEMPERATURE, FABRICATION, MCM-41
  • Yıldız Teknik Üniversitesi Adresli: Evet

Özet

The present study investigated drug release profiles from porous hydroxyapatite [Ca(5)(PO(4))(3)OH, HAP] tablets. HAP tablets prepared synthetically and porous structure was generated via microemulsion after sintering at 700 degrees C. The influence of tablet's microemulsion concentration on drug release profiles from sintered porous tablets was investigated by using ibuprofen (C(13)H(18)O(2)) as model drug.