Genome sequencing and analysis of the model grass Brachypodium distachyon

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Vogel J. P. , Garvin D. F. , Mockler T. C. , Schmutz J., Rokhsar D., Bevan M. W. , ...More

NATURE, vol.463, no.7282, pp.763-768, 2010 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 463 Issue: 7282
  • Publication Date: 2010
  • Doi Number: 10.1038/nature08747
  • Journal Name: NATURE
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.763-768


Three subfamilies of grasses, the Ehrhartoideae, Panicoideae and Pooideae, provide the bulk of human nutrition and are poised to become major sources of renewable energy. Here we describe the genome sequence of the wild grass Brachypodium distachyon (Brachypodium), which is, to our knowledge, the first member of the Pooideae subfamily to be sequenced. Comparison of the Brachypodium, rice and sorghum genomes shows a precise history of genome evolution across a broad diversity of the grasses, and establishes a template for analysis of the large genomes of economically important pooid grasses such as wheat. The high-quality genome sequence, coupled with ease of cultivation and transformation, small size and rapid life cycle, will help Brachypodium reach its potential as an important model system for developing new energy and food crops.