Within the scope of this study, it is aimed to contribute to the efforts for forming a database including the natural radiation levels throughout the country and developing a foundation for radiation safety. Karasu portion of the Euphrates valley within the provincial border of Erzincan was chosen for the investigation and natural radiation levels were detected by analyzing the samples taken in terms of radioactivity, natural environment’s radiation streams. Throughout the region of Karasu, 29 different samples from the water and 17 from the soil were taken and their total alpha, beta activities were detected. To take samples from the water and then they were measured by low background counter (Berthold brand LB770 10-channel counter). Total alpha and beta analyses were made according to the standard methods. Average values of alpha and beta concentrations of samples were measured as 0.0421 Bq/L and 1.806 Bq/L, respectively. For the soil samples HPGe gamma spectrometer system was used and radioisotope activity concentrations were found within the intervals of 2.7-27.8 Bq/kg for 226Ra; 3.2-39.4 Bq/kg for 232Th; 98-714 Bq/kg for 40K; < 0.4-57.8 Bq/kg for 137Cs, respectively. Different radioisotopes were detected in some of the samples taken from streaming beds joining river water.