Alveolar-capillary adaptation to chronic hypoxia in the fatty lung

Creative Commons License

Yilmaz C., RAVIKUMAR P., GYAWALI D., IYER R., UNGER R. H., HSIA C. C. W.

ACTA PHYSIOLOGICA, cilt.213, sa.4, ss.933-946, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 213 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/apha.12419
  • Dergi Adı: ACTA PHYSIOLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.933-946
  • Yıldız Teknik Üniversitesi Adresli: Evet

Özet

Aim: Obese diabetic (ZDF fa/fa) rats with genetic leptin resistance suffer chronic lipotoxicity associated with age-related lung restriction and abnormal alveolar ultrastructure. We hypothesized that these abnormalities impair adaptation to ambient hypoxia.