Akademik Veri Yönetim Sistemi
Carbon Nanotubes and Biomedicine, Rishabha Malviya,Selcan KarakuşORCID Icon,Sonali Sundram,Sathvik Belagodu Sridhar, Editör, Taylor & Francis Ltd, Florida, ss.81-97, 2025
The combination of developments in the area of nanotechnology with known technologies results in the exploitation of many benefits and innovations. Nanocarriers constitute one of the most significant of these innovations. The implementation of an effective and suitable carrier system is paramount for ensuring the efficient delivery of drugs into target cells. Smart drug delivery systems (SDDS) containing carbon nanotubes (CNTs) are regarded as a promising option in this domain because of their distinctive structural, chemical, and physical features. Because of their high surface area, durability, and capacity to penetrate cell membranes, CNTs have the opportunity to serve as successful carriers for targeted drug delivery. CNTs can be designed to selectively carry drugs to diseased cells, thereby minimizing systemic side effects and increasing therapeutic efficacy following the requirements of the medical field. Recent advances in the engineering and fabrication of CNT-based drug delivery systems have led to exploring their potential in treating various ailments such as cancer, neurologic disorders, and infections. Nevertheless, the use of CNTs presents several challenges in itself. These challenges include potential toxicity, difficulty in biodistribution, and cleaning difficulties. The future direction of CNT-based smart drug delivery systems lies in addressing these challenges through further research on biocompatibility and long-term safety. This review addresses the key attributes of CNTs that make them suitable for use in SDDS, such as biocompatibility, functionalization capabilities, and the ability to provide controlled and sustained release of therapeutic agents.