The process of scour around submarine pipelines laid on mobile beds is complicated due to physical processes arising from the triple interaction of waves/currents, beds and pipelines. This paper presents Artificial Neural Network (ANN) models for predicting the scour depth beneath submarine pipelines for different storm conditions. The storm conditions are considered for both regular and irregular wave attacks. The developed models use the Feed Forward Back Propagation (FFBP) Artificial Neural Network (ANN) technique. The training, validation and testing data are selected from appropriate experimental data collected in this study. Various estimation models were developed using both deep water wave parameters and local wave parameters. Alternative ANN models with different inputs and neuron numbers were evaluated by determining the best models using a trial and error approach. The estimation results show good agreement with measurements. (C) 2015 Elsevier Ltd. All rights reserved.