Enhanced Antifungal Activity of Electrosprayed Poly (vinyl alcohol)/Chitosan Nanospheres Loaded with Sage Essential Oil on the Viability of Aspergillus niger and Botrytis cinerea

Erarslan A., Karakaş C. Y., Bozkurt F., Sağdıç O.

CHEMISTRYSELECT, vol.8, no.21, pp.1-13, 2023 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 8 Issue: 21
  • Publication Date: 2023
  • Doi Number: 10.1002/slct.202300296
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Page Numbers: pp.1-13
  • Yıldız Technical University Affiliated: Yes


In this study, sage essential oil (SEO) loaded nanoparticles were tested in terms of their antifungal properties. In this respect, the electrospray method was employed to fabricate SEO-loaded nanoparticles (SNPs) by encapsulation of different concentrations (0.0, 0.25 %, 0.5 %, and 1 % v/v) of SEO within poly(vinyl alcohol)/chitosan-based nanoparticles (PVA/Chi NPs). The FTIR, DSC, and SEM analyses divulged that SEO could be successfully encapsulated within nanoparticles, possessing a spherical shape and high thermal stability. The encapsulation efficiency values of SNPs at different concentrations varied between 66.1 and 73.3 %. It was determined that SNPs released 62.56 % of their SEO content within 350 minutes. Moreover, the antifungal activity of SEO against Aspergillus niger and Botrytis cinerea could be increased significantly (p<0.05) after it was encapsulated into PVA/Chi NPs. Based on these findings, suggest that SNPs could be used in food preservation applications as a long-term and natural preservative given their controlled release properties.