SYNTHESIS OF BROMINATED QUINOLINES

Okten S., Eyigun D., ÇAKMAK O.

SIGMA JOURNAL OF ENGINEERING AND NATURAL SCIENCES-SIGMA MUHENDISLIK VE FEN BILIMLERI DERGISI, vol.33, no.1, pp.8-15, 2015 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 1
  • Publication Date: 2015
  • Journal Name: SIGMA JOURNAL OF ENGINEERING AND NATURAL SCIENCES-SIGMA MUHENDISLIK VE FEN BILIMLERI DERGISI
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals
  • Page Numbers: pp.8-15
  • Keywords: Quinoline, tetrahydroquinoline, bromoquinoline, bromination, aromatization, DDQ, DERIVATIVES, AGENTS
  • Yıldız Technical University Affiliated: Yes

Abstract

this study, bromination reactions of 1,2,3,4-tetrahydroquinoline by molecular bromine and aromatization reactions of brominated tetrahydroquinolines were reinvestigated. Optimal reaction conditions were established for 6-Bromo-1,2,3,4-tetrahydroquinoline (6-BrTHQ) and 6,8-dibromo-1,2,3,4-tetrahydroquinoline (6,8-diBrTHQ). Improved yields and more shortened reaction times were described for the conversion of 6-BrTHQ and 6,8-diBrTHQ into 6-bromoquinoline and 6,8-dibromoquinoline.