Reactions of 1,4-dianion of methyl 2-thienyl ketone N-ethoxycarbonylhydrazone with derivatives of carboxylic acids, and the synthesis of pyrazolotriazin-7-ones


Turgut Z. , Ocal N.

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, cilt.38, ss.602-605, 2002 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 38 Konu: 4
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1023/a:1016571828025
  • Dergi Adı: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
  • Sayfa Sayısı: ss.602-605

Özet

1,3,5-trisubstituted pyrazoles were obtained by reaction of carboxylic acids derivatives with 1,4-dianion of methyl 2-thienyl ketone N-ethoxycarbonylhydrazone. The dianion was prepared by treating the hydrazone with butyllithium in THF at -78degreesC. Besides were prepared 4-methyl (or 4-phenyl)-2-(2-thienyl)-6H-pyrazolo [1,5-d][1,2,4]triazin-7-ones from the corresponding 1,3,5-trisubstituted pyrazoles synthesized respectively, with the use of ethyl pyruvate and ethyl phenylglyoxylate.