BİLSEL INTERNATIONAL TURABDİN SCIENTIFIC RESEARCHES AND INNOVATION CONGRESS, 23 - 25 Ocak 2024, ss.679
This study describes a methodology for correcting specific physiological irregularities within a lung ventilation
model, with a focus on addressing tachycardia and increased respiratory resistance in conditions similar to
emphysema. Khoo's linear respiratory mechanics model was used to create a complete representation of both
central and peripheral airways. As an input, the framework uses airway opening pressure, and as an output, it
quantifies the volumetric flow rate of air into the alveoli. Pathophysiological states with increased volumetric
flow rates and respiratory resistance were used to simulate the abnormal conditions.
A multi-step approach was used to address this imbalance. To begin, a low-pass filter was used to reduce the
high-frequency respiratory patterns associated with arrhythmia. Following that, a Proportional-Integral (PI)
controller was added to the system to regulate the volumetric flow rate and return it to a more natural state. The
PI controller's parameters were determined using a Q-learning-based reinforcement-learning algorithm based on
the Bellman equation. This iterative process resulted in optimized controller parameters that were more
effective in correcting the simulated pathophysiological conditions.
Analyses of controller input-output responses and Integral Absolute Errors for each approach demonstrated the
efficacy of this methodology. The study presents a satisfactory lung ventilation model, demonstrating its ability
to effectively correct selected physiological disorders within the simulated environment.