In pharmaceutical chemistry, both N-heterocyclic compounds and metal carbonyl complexes are well-known
families because their several bioactivities. N-heterocyclics have been used biomedical and agricultural applications
while carbonyl complexes have been utilized for labelling biomolecules and releasing carbon monoxide.
Thus, the metal carbonyl derivatives with N-heterocyclic ligands have been researched. In this study [Mn
(CO)3(bpy)(1-phenylimidazole)]OTf and [Mn(CO)3(bpy)(1-(4-chlorophenyl)imidazole)]OTf [bpy:2,2′ -bipyridiyl,
OTf:SO3CF3) complexes were synthesized and characterized. CO-releasing properties, antioxidant and antibacterial
activities of these complexes were analyzed, and the bioactivity results were compared with DFT/TDFFT
and molecular docking methods. Additionally, the stability and activity of the molecules were investigated via
zetasizer and UV/VIS Spectroscopy.