CO-Releasing, Antioxidant, Antibacterial, Zeta Potential, Theoretical, and Electrochemical Analysis of [Mn(CO)3(bpy)L]OTf Type Complexes

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Üstün E., Şakar D., Çol Ayvaz M., Sönmez Çelebi M., Ertürk Ö.

POLYHEDRON, vol.224, no.115997, pp.1-9, 2022 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 224 Issue: 115997
• Publication Date: 2022
• Doi Number: 10.1016/j.poly.2022.115997
• Journal Name: POLYHEDRON
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core
• Page Numbers: pp.1-9
• Yıldız Technical University Affiliated: Yes

Abstract

In pharmaceutical chemistry, both N-heterocyclic compounds and metal carbonyl complexes are well-known

families because their several bioactivities. N-heterocyclics have been used biomedical and agricultural applications

while carbonyl complexes have been utilized for labelling biomolecules and releasing carbon monoxide.

Thus, the metal carbonyl derivatives with N-heterocyclic ligands have been researched. In this study [Mn

(CO)3(bpy)(1-phenylimidazole)]OTf and [Mn(CO)3(bpy)(1-(4-chlorophenyl)imidazole)]OTf [bpy:2,2′ -bipyridiyl,

OTf:SO3CF3) complexes were synthesized and characterized. CO-releasing properties, antioxidant and antibacterial

activities of these complexes were analyzed, and the bioactivity results were compared with DFT/TDFFT

and molecular docking methods. Additionally, the stability and activity of the molecules were investigated via

zetasizer and UV/VIS Spectroscopy.