The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3'UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population

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Tuten A., Aydemir B., Oncul M., Kiziler A. R., Acikgoz A. S., Korkmaz G. G., ...More

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.291, no.3, pp.563-571, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 291 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1007/s00404-014-3457-4
  • Journal Name: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.563-571
  • Yıldız Technical University Affiliated: Yes

Abstract

To investigate the main effect of polymorphisms in genes involved in endothelial pathophysiological mechanisms, LOX-1 K167N and 3'UTR188CT single nucleotide polymorphisms (SNPs) in relation to preeclampsia (PE) risk and possible interactions between the gene polymorphisms and plasma oxLDL and soluble LOX-1 (sLOX-1) levels on PE in Turkish population.