New and effective proline-based catalysts for asymmetric aldol reaction in water
SYNTHETIC COMMUNICATIONS, cilt.47, ss.78-85, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 47
- Basım Tarihi: 2017
- Doi Numarası: 10.1080/00397911.2016.1252988
- Dergi Adı: SYNTHETIC COMMUNICATIONS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.78-85
- Yıldız Teknik Üniversitesi Adresli: Evet
Özet
New proline diamide organocatalysts with Pro-Phe peptide bonds were synthesized and their catalytic activities in asymmetric direct aldol reactions of aliphatic ketones with aromatic aldehydes were investigated. Catalyst 6a showed good enantioselectivity at 0 degrees C in the presence of p-nitrobenzoic acid as cocatalyst in water.