Preparation of nanosized beta-tricalcium phosphate (β-TCP) based graft material for hard tissue applications

HAZAR A. B., Toraman A., Yürük E.

BIOMED 2017 22nd International Biomedical Science and Technology Symposium, Ankara, Turkey, 12 - 14 May 2017

  • Publication Type: Conference Paper / Summary Text
  • City: Ankara
  • Country: Turkey
  • Yıldız Technical University Affiliated: Yes


Calcium phosphates are the most important inorganic constituent of hard tissue. Hydroxyapatite and β-TCP are most commonly used materials in the biomedical application due to their close chemical similarity to the inorganic component of bone and teeth mineral. Owing to its resorbable features and excellent osteoconductive properties, β-TCP has found wide use as a implant material .

Pure-phase β-TCP is a suitable material for the filling of bone defects. The synthesis of pure β-TCP powders can be performed using either high-temperature solid-state reactions or wet precipitation methods. A chemical precipitation method at low temperature is recommended in order to obtain nanosize β-TCP powders. Nanosize β-TCP has an advantage over micro size powders leading to increased mechanical properties and sinterability.

β-tricalcium phosphate [β-TCP; Ca3(PO4)2] has received great attention as grafts for bone regeneration applications due to its excellent biocompatibility and biodegradability. 

In this study, pure-phase β-TCP has been synthesized using by modified synthesis method and produced graft material using by sponge method.