Comparative evaluation of denoising methods for off-axis digital holograms under realistic mixed-noise conditions

Abdioğlu H. B., Gursoy R., Isik Y., Balci İ. C., Esmer G. B., Uvet H., ...Daha Fazla

Optics Express, cilt.34, sa.7, ss.12687-12701, 2026 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 7
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1364/oe.591043
  • Dergi Adı: Optics Express
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Compendex, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.12687-12701
  • Yıldız Teknik Üniversitesi Adresli: Evet

Özet

Off-axis holographic microscopy enables single-shot quantitative phase imaging, but its sensitivity is limited by mixed noise that degrades fringe visibility and biases phase recovery. We compare classical filters (Wiener/median/NLM/BM3D and variance-stabilized variants), a supervised Swin transformer, and a diffusion denoiser trained on synthetic data, using 100,000 physics-based holograms with realistic blur, speckle, shot, and read noise. On a 10,000-hologram test set, the best pipeline (diffusion followed by BM3D) achieves 36.86 dB/0.9964 intensity PSNR/SSIM and 46.48 dB/0.9772 phase PSNR/SSIM, reducing RMSE by 88.5% in intensity and 52.8% in phase, with similar improvements on experimental bead and cell holograms.