Reactions of 2,2,6-Trimethyl-1,3-dioxin-4-one with the Aryl Aldimines Prepared from Thiophene-2-carbaldehyde


KOSER I., Ocal N. , Erden I.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.54, no.3, pp.1828-1832, 2017 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1002/jhet.2771
  • Title of Journal : JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Page Numbers: pp.1828-1832

Abstract

The reactions of aryl aldimines derived from thiophene-2-carbaldehyde (5-9) with 2,2,6-trimethyl-1,3-dioxin-4-one (1) were investigated. The new 1,3-oxazin-4-ones and thienylidene acetoacetamides were obtained in good yields. The synthetic utility of the latter via an intramolecular tandem Friedel-Crafts alkylation-acylation to give tetracyclic heterocyclic rings was also explored.