Biotransformation of racemic diisophorone by Cephalosporium aphidicola and Neurospora crassa


Kiran I., Akar T., Gorgulu A. , Kazaz C.

BIOTECHNOLOGY LETTERS, cilt.27, ss.1007-1010, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 27 Konu: 14
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s10529-005-7868-y
  • Dergi Adı: BIOTECHNOLOGY LETTERS
  • Sayfa Sayıları: ss.1007-1010

Özet

Racemic diisophorone (500 mg) was converted by Cephalosporium aphidicola and Neurospora crassa over 10 days at 25 degrees C to 8 beta-hydroxydiisophorone in yields of 10% (52 mg) and 20% (103 mg), respectively. The structure was established by IR, specific rotation, mass spectral, 1D and 2D-NMR studies.