Solvent Free Synthesis of N-Substituted Pyrrole Derivatives Catalyzed by Silica Sulfuric Acid


Khammas A. J. , Yolaçan Ç. , Aydoğan F.

RUSSIAN JOURNAL OF GENERAL CHEMISTRY, vol.88, pp.2680-2683, 2018 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 88
  • Publication Date: 2018
  • Doi Number: 10.1134/s1070363218120332
  • Title of Journal : RUSSIAN JOURNAL OF GENERAL CHEMISTRY
  • Page Numbers: pp.2680-2683

Abstract

Sulfuric acid immobilized on silica gel is used as an efficient catalyst in the synthesis of N-substituted pyrrole derivatives by the Clauson-Kaas pyrrole synthesis. The solvent free reaction mixture is stirred by grinding. Within very short reaction time the process leads to the corresponding products without any decomposition recorded.