Differential Pulse Voltammetric Determination of Serotonin Using an Acid-Activated Multiwalled Carbon Nanotube - Over-Oxidized Poly(3,4-ethylenedioxythiophene) Modified Pencil Graphite Electrode


GÖRDÜK Ö.

ANALYTICAL LETTERS, vol.53, no.7, pp.1034-1052, 2020 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 7
  • Publication Date: 2020
  • Doi Number: 10.1080/00032719.2019.1693583
  • Title of Journal : ANALYTICAL LETTERS
  • Page Numbers: pp.1034-1052

Abstract

In this study, acid-activated multi-walled carbon nanotubes (AA-MWCNT) and poly(3,4-ethylenedioxythiophene) (PEDOT) were deposited on a pencil graphite electrode (PGE) surface for electrochemical sensing applications. The acid-activated multi-walled carbon nanotube/over-oxidized poly(3,4-ethylenedioxythiophene) modified pencil graphite electrode (AA-MWCNT/OO-PEDOT/PGE) was characterized using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and X-ray photoelectron spectroscopy (XPS). The sensing properties of the obtained surface were examined for the voltammetric determination of serotonin in a phosphate buffer solution. The effects of the pH, adsorption time, over-oxidation and polymerization parameters on the electrochemical properties of serotonin were investigated. The effects of possible interfering substances were evaluated. The detection limit was determined to be 0.092 mu M based on a signal-to-noise ratio of 3. Analytical applications of AA-MWCNT/OO-PEDOT/PGE were successfully tested for the determination of serotonin in human blood serum samples.