40. Yöneylem Araştırması ve Endüstri Mühendisliği Kongresi, İstanbul, Türkiye, 4 - 07 Temmuz 2021, ss.112
Increasing antibiotic resistance is expected to be one of the
most important health care problems of the modern world.
Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when bacteria
evolve in response to the use of these medicines. It is the
ability of bacteria to resist the effects of an antibiotic to
which they were once sensitive. Due to antibiotic resistance,
the effectiveness of antibiotics decreases. Accordingly, the
duration of treatment is extended, the hospital stays are increased, and a decrease in recovery is observed. In addition
to these, it causes undesired consequences on the economy
and human health. It is known that one of the main reasons
for antibiotic resistance is excessive antibiotic consumption.
As most respiratory diseases result from non-bacterial infections, most antibiotics are used when they are not required.
Unnecessary prescriptions can be reduced by educating the
doctors and society on antimicrobial resistance, and making
testing widely available to identify whether the infection is
bacterial or nonbacterial. However antibiotic resistance is
a complex problem with many nonlinear relationships furthermore, causes and effects are distant in time and space.
Therefore, modeling approaches can help decision makers to
understand the problem and take necessary actions. Many
countries around the world suffer from the antibiotic resistance problem yet, the situation in Turkey is critic. Turkey
is the country, where most of the antibiotics consumed in
Europe. Moreover, Turkey is the second country with the
highest antibiotic resistance. In this study, Turkey’s antibiotic resistance level is modeled by using the system dynamics
approach. This model is simulated over the years, and several
policies to reduce antibiotic resistance levels are analyzed. In
policy analyses it is observed that the most effective interventions are achieved by combined policies.