Unraveling the KNOTTED1 regulatory network in maize meristems

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Bolduc N., Yilmaz A., Mejia-Guerra M. K., Morohashi K., O'Connor D., Grotewold E., ...Daha Fazla

GENES & DEVELOPMENT, cilt.26, sa.15, ss.1685-1690, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 15
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1101/gad.193433.112
  • Dergi Adı: GENES & DEVELOPMENT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1685-1690
  • Yıldız Teknik Üniversitesi Adresli: Evet

Özet

KNOTTED1 (KN1)-like homeobox (KNOX) transcription factors function in plant meristems, self-renewing structures consisting of stem cells and their immediate daughters. We defined the KN1 cistrome in maize inflorescences and found that KN1 binds to several thousand loci, including 643 genes that are modulated in one or multiple tissues. These KN1 direct targets are strongly enriched for transcription factors (including other homeobox genes) and genes participating in hormonal pathways, most significantly auxin, demonstrating that KN1 plays a key role in orchestrating the upper levels of a hierarchical gene regulatory network that impacts plant meristem identity and function.