Akademik Veri Yönetim Sistemi
The Third Anatolian Conference on Organic Chemistry, Antalya, Türkiye, 13 - 16 Mart 2023, ss.40
Coumarins and their analogues are not only known for their excellent biological activities but
also well known for their outstanding optical properties. Coumarins show good spectral
response, have high photostability and are also recognised as highly efficient fluorophores with
high quantum yield, decent extinction coefficient and large Stokes shift. Moreover, because of
such exceptional optical properties, coumarin derivatives are known to find a diverse range of
applications as fluorescent dyes, fluorescent probes, emission layers in organic light-emitting
diodes (OLED), optical brighteners, nonlinear optical chromophores, fluorescent whiteners,
fluorescent indicators, optical recording and solar energy collectors. In contrast to the general
instrumental methods, fluorescence analyses have many outstanding features under
physiological conditions, such as high sensitivity or selectivity, simple manipulations, low cost,
rapid response rate, real-time detection, spatiotemporal resolution and facile visualization.
Coumarin derivatives can be used as fluorescent probes for metal ions due to their highly
variable size, hydrophobicity, and chelation[1][2]
.
In conclusion, coumarins are of tremendous interest because they exhibit a variety of
pharmacological actions, excellent photophysical and photochemical properties. Therefore,
many coumarin derivatives have been synthesized and used successfully in fluorescent
chemosensor applications to detect different cations and anions in various medium. In this
study, a new coumarin based Schiff base chemosensor for fluorescence detection of Zn2+ was
designed and synthesized and its photophysical properties were investigated[3]
.