SIMULTANEOUS DETERMINATION OF ACETAMINOPHEN AND PHENOBARBITAL IN SUPPOSITORIES BY PARTIAL LEAST-SQUARES SPECTROPHOTOMETRIC CALIBRATION
ANALYTICAL LETTERS, cilt.25, sa.11, ss.2051-2058, 1992 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 25 Sayı: 11
- Basım Tarihi: 1992
- Doi Numarası: 10.1080/00032719208020074
- Dergi Adı: ANALYTICAL LETTERS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.2051-2058
- Yıldız Teknik Üniversitesi Adresli: Evet
Özet
The use of partial least-squares spectrophotometric calibration for the simultaneous determination of suppositories in a multicomponent formulation is presented. This method is applied to the determination of acetaminophen and phenobarbital in suppository preparations. The results show that these components in a molar ratio of about 61:1 in suppositories have been determined simultaneously with high precision.