The west part of Turkey has great potential for geothermal energy resources. The exploitation of this potential in the Denizli-Kizildere geothermal energy region depends on the removal of its high boron content since waste brine is discharged into the nearby River Buyuk Menderes. This river is an important source of agricultural irrigation, so consideration must be given to the amount and quality of the added geothermal waste water. A study is made of boron removal from Kizildere/Turkey geothermal wastewater using ion exchange resin. The use of ion exchange resin for the removal of boron from wastewaters requires expensive regeneration steps. A three stage acid regeneration process has been investigated to find the optimal operational conditions for minimizing the regenerant consumption. Boron removal after three stage acid regeneration with 5% H2SO4 is possible since the wastewater of the Kizildere geothermal field has enough buffering capacity to neutralize the released add from the resin.