Parkin level in plasma of ALS patients
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, cilt.22, ss.105, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22
- Basım Tarihi: 2021
- Dergi Adı: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
- Sayfa Sayıları: ss.105
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Yıldız Teknik Üniversitesi Adresli: Evet
Özet
Accumulation of misfolded and damaged pro-
teins are known to be associated with the pathogenesis of
many neurodegenerative diseases such as Parkinson ’ s
Disease, Alzheimer Disease, ALS (1 – 4). Parkin, an E3 ubiquitin-
protein ligase, is an important component of ubiquitin-prote-
asome system (5). It is known that Parkin is important for
especially genetic Parkinsonism. There is limited study on
Parkin for ALS disease.