Antimicrobial activity studies of the binuclear metal complexes derived from tridentate Schiff base ligands


Tumer M., Koksal H., Sener M. , Serin S.

TRANSITION METAL CHEMISTRY, vol.24, no.4, pp.414-420, 1999 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 4
  • Publication Date: 1999
  • Doi Number: 10.1023/a:1006973823926
  • Title of Journal : TRANSITION METAL CHEMISTRY
  • Page Numbers: pp.414-420

Abstract

Three novel tridentate Schiff base ligands derived from the 3-hydroxysalicylaldehyde (H2L1), 4-hydroxysalicylaldehyde (H2L2) and 5-bromosalicylaldehyde (H2L3) with a new amine N-(pyridyl)-2-hydroxy-3-methoxy-5-aminobenzylamine (2) have been prepared. The ligands and their metal complexes have been characterized by elemental analyses, conductivity and magnetic susceptibility measurements, i.r., electronic absorption and H-1 and C-13 n.m.r. spectroscopy. All complexes are binuclear and, in some, the H2O molecules are coordinated to the metal ion. Antimicrobial activities of the ligands and their complexes have been tested against to the Bacillus subtilis IMG 22 (bacteria), Micrococcus luteus LA 2971 (bacteria) Saccharamyces cerevisiae WET 136 (yeast), and Candida albicans CCM 314 (yeast). Thermal properties of all complexes have been studied by t.g. and d.t.a techniques.