Synthesis of New Thiazolidine Based Organocatalysts and their Application to Asymmetric Aldol Reaction

Cicek M., Aydoğan F., Yolaçan Ç.

LETTERS IN ORGANIC CHEMISTRY, vol.14, pp.778-786, 2017 (SCI-Expanded) identifier identifier


Background: Proline and its derivatives are versatile organocatalysts for many reactions. Especially prolinamide derivatives have been prepared and investigated in aldol reaction successfully. Generally, derivatizations have been made on side chain of proline to develop new effective catalysts. But, there are only few examples of different cyclic systems other than pyrrolidine ring used as chiral organocatalysts.