NANO, cilt.17, sa.1, ss.22500141-22500149, 2022 (SCI-Expanded)
A copper oxide (CuO) nanoparticle, a transition metal oxide with a wide variety of easy production
methods, can be used as an antimicrobial agent against various types of bacteria. CuO
nanoparticles were produced by the sol–gel method, annealed and structural characteristics and
antimicrobial properties of these particles were investigated. Single-phase monoclinic of CuO
nanoparticle formation was con¯rmed by X-ray powder di®raction (XRD) spectra, FTIR techniques,
di®erential scanning calorimetry with thermal gravimetry were used to characterize. It
was determined that annealing in the temperature range of 150–900C a®ects both structure and
particle size and antimicrobial characteristics. CuO nanoparticle size was found to be between
about 25–70 nm at 150–900C annealing temperature, which does not have this wide temperature
range in the literature. These results were supported by the TEM micrographs of the CuO
nanoparticles observed at 150C and 900C. The antimicrobial activity of the synthesized
nanoparticles was tested with the disc di®usion assay against Staphylococcus aureus, Escherichia
coli, Agrobacterium tumefaciens, and yeast Pichia pastoris.