7th International Conference on Advances in Natural& Applied Science, Antalya, Türkiye, 16 - 20 Nisan 2024, ss.40-41
Garlic, scientifically known as Allium sativum, is a plant belonging to the Liliaceae family.
It has been used for many years due to its diverse biological and therapeutic
characteristics. These vegetables are rich in organosulfur compounds (OSCs)1,2,3. The
aim of this study is to investigate the anticancer effects of natural organosulfur
compounds originating from our country. The anticancer properties of Kastamonu
Taşköprü garlic were assessed applying both water-soluble and oil-soluble extraction
techniques. Anticancer effects were examined on NIH/3T3 (ATCC; CRL-1658), Caco-2
human colorectal cancer (ATCC; HTB-37), and MCF-7 human breast cancer (ATCC; HTB-
22) cell lines. According to these extraction methods, the cell viability and cytotoxic
effects of the extractions were analysed. As a result of the examination of anticancer
effects, it was determined that the anticancer effects of Kastamonu Taşköprü garlic
soluble in oil had higher anticancer effects than water-soluble garlic extracts.