The application of the sinc-Galerkin method to an approximate solution of second-order singular Dirichlet-type boundary value problems were discussed in this study. The method is based on approximating functions and their derivatives by using the Whittaker cardinal function. The differential equation is reduced to a system of algebraic equations via new accurate explicit approximations of the inner products without any numerical integration which is needed to solve matrix system. This study shows that the sinc-Galerkin method is a very effective and powerful tool in solving such problems numerically. At the end of the paper, the method was tested on several examples with second-order Dirichlet-type boundary value problems.