Highly Sensitive Electrochemical Determination of Dopamine with an Overoxidized Polypyrrole Nanofiber Pencil Graphite Electrode
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, vol.12, no.7, pp.6428-6444, 2017 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 12 Issue: 7
- Publication Date: 2017
- Doi Number: 10.20964/2017.07.41
- Journal Name: INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.6428-6444
- Keywords: Dopamine, Polypyrrole, Electropolymerization, Pencil Graphite Electrode, Sensor, GLASSY-CARBON ELECTRODE, ASCORBIC-ACID, URIC-ACID, GRAPHENE OXIDE, SELECTIVE DETERMINATION, PASTE ELECTRODE, GOLD ELECTRODE, SERUM SAMPLES, NANOTUBES, SENSOR
- Open Archive Collection: AVESIS Open Access Collection
- Yıldız Technical University Affiliated: Yes
Abstract
We investigated the use of an overoxidized nanofiber polypyrrole (OONfPPy) modified pencil graphite electrode (PGE) as a sensor for the determination of dopamine (DA) in this work. The performance of the modified electrode was studied using differential pulse voltammetric method. The surface of the modified electrode was characterized by an electrochemical impedance spectroscopy (EIS) and scanning electron microscope (SEM). The calculated electroactive areas of the bare electrode and OO(10)NfPPy(5)PGE were found to be 4.54 x 10(-8) cm(2) and 1.05 x 10(-6) cm(2), respectively. The sensor (OO(10)NfPPy(5)PGE) showed a high selectivity to DA with a detection limit of 6.95 x 10(-9) M (S/N= 3). To demonstrate the validity of the sensor for the determination of DA, pharmaceutical and human serum samples were performed.