in: Innovations in Chemical Biology, Bilge Şener, Editor, Netherlands Library Service , Dordrecht, pp.411-419, 2008
Abstract Heterocyclic compounds containing atoms of the elements such as nitrogen,
sulfur and oxygen as ring members are commonly used in various fields of
industry as analytical reagents, ligands, dyestuffs, pharmaceutical substances and
bioindicators.
In this study 5-(Quinoline-2-ylidene)-1,3-diethyl-2-thiobarbituric acid have been
synthesized via Knoevenagel condensation reaction , the product solutions were prepared
10 -3 – 10 -5 M in CHCI 3 , THF, MeOH, DMF and DMSO. UV/VIS spectra
recorded and then compared at each other. Absorbance of the solutions were measured
at 200 – 300 nm. The maximum absorbance value increased and a new absorption
appeared at 400 – 500 nm. The samples were excited at 337 nm in order to measure
fluorescence. The maximum emission was observed in MeOH at 398 nm. These values
increased by time; therefore, the samples were not stable in solution state.