Nano-Bioceramic Production From Marine Source

YÜCEL S. , Orman Z., Şahin Y. M. , Oktar F. N. , Gündüz O.

International Advanced Researches and Engineering Congress, Osmaniye, Turkey, 16 November 2017, pp.2534

  • Publication Type: Conference Paper / Summary Text
  • City: Osmaniye
  • Country: Turkey
  • Page Numbers: pp.2534


Bone diseases and disabilities such as joint pathologies, fractures related to osteoporosis affect many people worldwide.These problems are currently treated with bone grafts, in particular autografts and allografts or on replacement with prostheses and fixation devices using metal, polymer and ceramic material systems [1]. Calcium phosphate ceramics are biocompatible and biodegradable biomaterials that can be different combinations. Calcium phosphate ceramics such as hydroxyapatite (HA) and tricalcium phosphate (TCP) are used for metallic implants coatings for bone grafts, drug delivery, and bone regeneration. HA is very attractive calcium apatite since it is in the bone itself. It is highly bioactive and biocompatible with bone and it helps to bone regeneration [2]. Calcium phosphate materials are produced from many natural  materials, sea shells, animal bones via dry synthesis, wet chemical, sol-gel, emulsion method, mechanochemical methods [3]. There is not an ideal method for producing calcium ceramic material for bone grafting. Production methods allow obtaining of an appropriate material surface, crystal structure and proper Ca/P molar ratio. HA is commonly used in non-load bearing applications and β-TCP is used for load-bearing applications since β-TCP is slowly dissolved and is resorbed from body and replaced by surrounding tissue [4]. Calcium phosphate ceramics are used as bone filler material in the repair of bone fractures, cracks or defects by forming HA layer between implant and surrounding tissue. Calcium phosphate ceramics have various advantages such as their resistance to corrosion, low electrical and thermal conductivity and high compressive strength. It has been reported that porosity of HA ceramics are important in bone ingrowth since porosity of surface increase the cell adhesion and proliferation [5]. 

Calcium phosphate ceramics can be obtained from different resources. In this study, sea snail Turritella terebra was used as a source of calcium and was converted to calcium phosphate apatites by mechanochemical method. The materials were transformed to various bioceramic phases at four varying temperature of 450°C, 850°C, 1000°C and 1200°C. For complete characterization of the produced bioceramics Fourier Transform Infrared Spectroscopy (FT-IR) and x-ray diffraction (XRD), differential thermal analysis (TG/DTA).