Application of Grobner basis techniques to enzyme kinetics
APPLIED MATHEMATICS AND COMPUTATION, cilt.153, sa.1, ss.97-109, 2004 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 153 Sayı: 1
- Basım Tarihi: 2004
- Doi Numarası: 10.1016/s0096-3003(03)00612-x
- Dergi Adı: APPLIED MATHEMATICS AND COMPUTATION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.97-109
- Yıldız Teknik Üniversitesi Adresli: Hayır
Özet
It is possible to write down the equations governing a one-stage enzyme-catalysed reaction (according to Michaelis-Menten kinetics) quite easily, and deduce information about the steady-state flux in such a system. The situation is somewhat more complicated if several such reactions form a linear chain. We have applied Grobner basis techniques to solve such systems and hence demonstrate the use of computer algebra as a powerful technique in enzyme kinetic analysis. (C) 2003 Elsevier Inc. All rights reserved.