Application of Grobner basis techniques to enzyme kinetics


Celik E., Bayram M.

APPLIED MATHEMATICS AND COMPUTATION, vol.153, no.1, pp.97-109, 2004 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 153 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1016/s0096-3003(03)00612-x
  • Title of Journal : APPLIED MATHEMATICS AND COMPUTATION
  • Page Numbers: pp.97-109

Abstract

It is possible to write down the equations governing a one-stage enzyme-catalysed reaction (according to Michaelis-Menten kinetics) quite easily, and deduce information about the steady-state flux in such a system. The situation is somewhat more complicated if several such reactions form a linear chain. We have applied Grobner basis techniques to solve such systems and hence demonstrate the use of computer algebra as a powerful technique in enzyme kinetic analysis. (C) 2003 Elsevier Inc. All rights reserved.