Application of Grobner basis techniques to enzyme kinetics


Celik E., Bayram M.

APPLIED MATHEMATICS AND COMPUTATION, cilt.153, ss.97-109, 2004 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 153 Konu: 1
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/s0096-3003(03)00612-x
  • Dergi Adı: APPLIED MATHEMATICS AND COMPUTATION
  • Sayfa Sayıları: ss.97-109

Özet

It is possible to write down the equations governing a one-stage enzyme-catalysed reaction (according to Michaelis-Menten kinetics) quite easily, and deduce information about the steady-state flux in such a system. The situation is somewhat more complicated if several such reactions form a linear chain. We have applied Grobner basis techniques to solve such systems and hence demonstrate the use of computer algebra as a powerful technique in enzyme kinetic analysis. (C) 2003 Elsevier Inc. All rights reserved.