Evaluation of in vitro and in vivo immunostimulatory activities of poly (lactic-co-glycolic acid) nanoparticles loaded with soluble and autoclaved Leishmania infantum antigens: A novel vaccine candidate against visceral leishmaniasis


Abamor E. Ş. , Allahverdiyev A. , Tosyali O. A. , Bağırova M. , Acar T., Mustafaeva Z., ...Daha Fazla

ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, cilt.12, sa.8, ss.353-364, 2019 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Konu: 8
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4103/1995-7645.262564
  • Dergi Adı: ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE
  • Sayfa Sayıları: ss.353-364

Özet

Objective: To prepare and characterize poly lactic-co-glycolic acid (PLGA) nanoparticles loaded with soluble leishmanial antigen or autoclaved leishmanial antigen and explore in vitro and in vivo immunogenicity of antigen encapsulated nanoparticles.