Evaluation of in vitro and in vivo immunostimulatory activities of poly (lactic-co-glycolic acid) nanoparticles loaded with soluble and autoclaved Leishmania infantum antigens: A novel vaccine candidate against visceral leishmaniasis

Abamor, Emrah; Allahverdiyev, ADİL; Tosyali, Ozlem; Bağırova, MELAHAT; Acar, Tayfun; Mustafaeva, Zeynep; Derman, Serap

doi:10.4103/1995-7645.262564

Evaluation of in vitro and in vivo immunostimulatory activities of poly (lactic-co-glycolic acid) nanoparticles loaded with soluble and autoclaved Leishmania infantum antigens: A novel vaccine candidate against visceral leishmaniasis

Atıf İçin Kopyala

Abamor E. Ş. , Allahverdiyev A. , Tosyali O. A. , Bağırova M. , Acar T., Mustafaeva Z., ...Daha Fazla

ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, cilt.12, ss.353-364, 2019 (SCI İndekslerine Giren Dergi)

Cilt numarası: 12 Konu: 8
Basım Tarihi: 2019
Doi Numarası: 10.4103/1995-7645.262564
Dergi Adı: ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE
Sayfa Sayıları: ss.353-364

Özet

Objective: To prepare and characterize poly lactic-co-glycolic acid (PLGA) nanoparticles loaded with soluble leishmanial antigen or autoclaved leishmanial antigen and explore in vitro and in vivo immunogenicity of antigen encapsulated nanoparticles.