Polarographic determination of fluvoxamine maleate in tablets


ELMALI F. , Alpdogan G. , SUNGUR S. , AYCAN S.

TURKISH JOURNAL OF CHEMISTRY, cilt.24, ss.299-302, 2000 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 24 Konu: 3
  • Basım Tarihi: 2000
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Sayfa Sayısı: ss.299-302

Özet

The differential pulse polarographic (DPP) method was developed for the determination of fluvoxamine maleate (I). At pH = 3. 7, (I) give a peak at - 0. 73 V in aqueous solution. The developed method was applied to the assay of the drug substance in commercial tablet formulations. The results were statistically compared with those obtained by reference methods (HPLC and direct current polarographic method) using t- and F- tests at 95 % confidence level.